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Item
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Specifications
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Appearance
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White lyophilized powder
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Purification method
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The liquid phase layer analysis
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Identification
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The sample retention time conformed to that of standard sample
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Purity
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98% min
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Water
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≤3.0%
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The colony counting
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Undetectable
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Sterility
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BP
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Bacterial endotoxins
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≤ 5.0IU/ mg
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Lr3IGF-1 (Long R3 Insulin-like Growth Factor-I or Long R3IGF-I) is an 83 amino acid analog of human IGF-I actually comprising the complete human IGF-1 sequence but with the substitution of an Arg for the Glu at position 3, as well as a 13 amino acid extension peptide at the N-terminus. This makes Long R3IGF-I significantly more potent (2-3x) than IGF-I in studies, because it has a lower affinity to be rendered inactive by IGF binding proteins, and consequently more potential activity in the body.
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